Many commercially available biologics, previously delivered only intravenously, are being re-formulated for subcutaneous delivery to improve patient access and compliance.However, due to inherent solubility limitations, large volume injections (more than 2 mL) are typically required.Different strategies are being explored to improve the tolerabilit
Subacute combined degeneration from nitrous oxide abuse
Nitrous oxide is an anesthetic medication which can also be recreationally abused in the form of whippet canisters.Its prolonged abuse can interfere with Vitamin B12 metabolism and lead to its functional deficiency.We report a case of a 30-year-old male who presented with generalized weakness and was Cardiovascular Fitness Profile of Sleman Regency
Introgression Breeding in Barley: Perspectives and Case Studies
Changing production scenarios resulting from unstable climatic conditions are challenging crop improvement efforts.A deeper and more practical understanding of plant genetic resources is necessary if these Acinar ATP8b1/LPC pathway promotes macrophage efferocytosis and clearance of inflammation during chronic pancreatitis development assets are to
Ultranarrow-linewidth stimulated Brillouin scattering with fundamental acoustic waves
Stimulated Brillouin scattering is a well-known nonlinear optical interaction valued for applications including narrow-linewidth lasers, phase conjugation, sensing, and RF-signal processing such as delay lines and filters.While interaction strength and linewidth directly affect device performance, most strongly interacting Brillouin systems have li
Integrative analysis of anoikis-related prognostic signature to evaluate the immune landscape and predict therapeutic response in stomach adenocarcinoma
Abstract Stomach adenocarcinoma (STAD) is the most prevalent gastrointestinal malignancy and seriously threatens the life of the global population.Anoikis, a process of programmed cell death that occurs when cells detach from the extracellular matrix, is closely associated with tumor invasion and metastasis.In this study, we used the TCGA-STAD data